protein

Neuroserpin Protein, Mouse (HEK293, His)

HY-P74703

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

Neuroserpin Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

Neuroserpin is a serine protease inhibitor that significantly inhibits plasminogen activator and plasmin without affecting thrombin.In addition to their role in protease inhibition, neuroserine proteases contribute to synaptic plasticity, affecting synaptic connections in the adult nervous system.Neuroserpin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Neuroserpin protein, expressed by HEK293 , with C-His labeled tag.

Mouse

Neuroserpin, a serine protease inhibitor, plays a crucial role in inhibiting plasminogen activators and plasmin, with no inhibitory effect on thrombin. Beyond its role as a protease inhibitor, it is implicated in the formation or reorganization of synaptic connections, contributing to synaptic plasticity in the adult nervous system. Additionally, there is a suggested protective role for neuroserpin in safeguarding neurons from cell damage mediated by tissue-type plasminogen activator. These functions underscore the significance of neuroserpin in regulating proteolytic activities and maintaining neuronal integrity in the intricate network of synaptic processes.

Neuroserpin; Peptidase inhibitor 12; Serpin I1; SERPINI1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.