protein

Nicastrin Protein, Human (HEK293, His)

HY-P74698

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

Nicastrin Protein, Human (HEK293, His)

Protein

HEK293

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

Nicastrin Protein, a crucial gamma-secretase complex subunit, catalyzes intramembrane cleavage of Notch receptors and APP.Operating in Notch and Wnt signaling, the complex modulates regulatory proteins and CTNNB1 levels.Collaborating with PSEN1/2, APH1A/B, and PSENEN/PEN2, Nicastrin binds to proteolytically processed C83 and C99 fragments, emphasizing its pivotal role in molecular pathways and cellular processes.Nicastrin Protein, Human (HEK293, His) is the recombinant human-derived Nicastrin protein, expressed by HEK293 , with C-His labeled tag.