protein

Nucleoprotein/NP Protein, H1N1 (I116M, AAM75159, sf9, His)

HY-P74676

50 μg

420 USD

Nucleoprotein/NP Protein, H1N1 (I116M, AAM75159, sf9, His)

proteins

Sf9 insect cells

50 μg

420 USD

Influenza virus nucleoprotein (NP) is a structural protein that coats viral negative-strand RNA.NP proteins protect viral RNA from degradation by cellular enzymes during the viral life cycle, fit the helical structure of RNP, regulate transcription and replication of viral RNA templates in a histone-like manner, and induce immunosuppression during infection.Nucleoprotein/NP Protein, H1N1 (I116M, AAM75159, sf9, His) is the recombinant Virus-derived Nucleoprotein/NP protein, expressed by Sf9 insect cells , with C-His labeled tag.

Virus

Influenza virus nucleoprotein (NP) is a structural protein that coats viral negative-strand RNA. NP is one of the main determinants of species specificity. The extent to which NP genes can be reprogrammed to cross the species barrier and adapt to a new host by mutation. NP proteins protect viral RNA from degradation by cellular enzymes during the viral life cycle, fit the helical structure of RNP, regulate transcription and replication of viral RNA templates in a histone-like manner, and induce immunosuppression (inhibition of effector cytokine synthesis and FcR drug signaling) during infection. NP is a very promising target for future vaccine development [1] [2] .

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein / NP (I116M) Protein (sf9, His)

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 60 mM Tris, 500 mM NaCl, 10% Glycerol, pH 7.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.