protein

Nucleoside phosphorylase/PNP Protein, Human (His)

HY-P74665

5 μg;10 μg;50 μg

135;232;650 USD

Nucleoside phosphorylase/PNP Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg

135;232;650 USD

Nucleoside phosphorylase/PNP proteins play a vital role in cellular processes by catalyzing the phosphate breakdown of β-(deoxy)ribonucleosides, preferably 6-oxopurine nucleosides, such as inosine and guanosine. This enzymatic activity results in the formation of free purine bases and pentose 1-phosphate, highlighting the importance of this protein in regulating nucleoside degradation. Nucleoside phosphorylase/PNP Protein, Human (His) is the recombinant human-derived Nucleoside phosphorylase/PNP protein, expressed by E. coli , with C-10*His labeled tag. The total length of Nucleoside phosphorylase/PNP Protein, Human (His) is 289 a.a., with molecular weight of ~33.5 kDa.

Human

The Nucleoside phosphorylase/PNP protein assumes a crucial role in cellular processes by catalyzing the phosphorolytic breakdown of N-glycosidic bonds in beta-(deoxy)ribonucleoside molecules. This enzymatic activity results in the formation of the corresponding free purine bases and pentose-1-phosphate, as documented in relevant literature. Notably, the protein exhibits a preference for 6-oxopurine nucleosides, such as inosine and guanosine. The substrate specificity of Nucleoside phosphorylase/PNP underscores its significance in the regulated degradation of nucleosides, providing insights into its role in maintaining cellular purine homeostasis and contributing to the overall dynamics of nucleotide metabolism.

Purine nucleoside phosphorylase; PNP; Inosine phosphorylase; NP

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.2 μm filtered solution of PBS, 25% glycerol, pH 7.5 or 50 mM Tris-HCL, 300 mM NaCl, 200 mM arginine, pH 8.0.

Room temperature in continental US; may vary elsewhere.