AGR3 Protein, Human (HEK293, His) | MedChem Express LLC HY-P7466 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

AGR3 Protein, Human (HEK293, His)

catalog :

HY-P7466

quantity :

10 μg;50 μg

price :

107;300 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7466

Product Name :

AGR3 Protein, Human (HEK293, His)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

107;300 USD

list of Pubmed id :

405076100

Product Description :

AGR3 Protein, Human (HEK293, His) is human recombinant AG-3 with a N-terminal His tag. AG-3 Protein, Human (HEK293, His) is expressed in HEK293 cells.

SpeciesSummary :

Human

Background :

AGR3 (Anterior gradient 3; AG-3), a member of the protein disulfide isomerase (PDI) family, shares high sequence homology with AG-2. AGR3 is overexpressed in breast, prostate and ovarian cancer. Combined AGR3 and acid mucopolysaccharides could serve as a diagnostic marker for well-differentiated intrahepatic cholangiocarcinoma. AGR3 expression was correlated with the level of differentiation in the serous type of ovarian cancer. AGR3 activates Wnt/β-catenin signalling and promotes the nuclear translocation of β-catenin to upregulate stemness related genes [1] .

ALTnames :

rHuAG-3, His; HAG-3; AGR3; AG3; Anterior gradient protein 3

Purity :

Greater than 90% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against 20 mM Tris-HCl, 150 mM NaCl, 2 mM EDTA, pH 8.5 or 20 mM Glycine-HCl, 10% Trehalose, 0.05% Tween80, pH 3.5.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage