protein

AG-2 Protein, Human (HEK293, His)

HY-P7465A

5 μg;10 μg;50 μg;100 μg

50;84;235;400 USD

AG-2 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

50;84;235;400 USD

AG-2 protein is critical for MUC2 post-transcriptional synthesis and secretion, implicating its role in intestinal mucus production. As a proto-oncogene, AG-2 affects cell migration, differentiation, and growth. AG-2 Protein, Human (HEK293, His) is the recombinant human-derived AG-2 protein, expressed by HEK293 , with C-10*His labeled tag.

Human

AG-2 protein is essential for the post-transcriptional synthesis and secretion of MUC2, suggesting a potential involvement in mucus production by intestinal cells. Beyond its role in mucin regulation, AG-2 emerges as a proto-oncogene, exerting influence on cell migration, differentiation, and growth. Notably, AG-2 promotes cell adhesion, underscoring its multifaceted contributions to cellular processes. Structurally, AG-2 exists as both a monomer and a homodimer. Additionally, it interacts with LYPD3 and DAG1 (alphaDAG1), forming complexes that may further modulate its functions. The interaction with MUC2, characterized by disulfide linkages, highlights the intricate molecular relationships AG-2 establishes within the cellular milieu.

rHuAG-2, His; HPC8; AGR2; AG2

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.