product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
AG-2 Protein, Human (HEK293, His, solution)
catalog :
HY-P7465
quantity :
10 μg;50 μg
price :
125;350 USD
product information
Catalog Number :
HY-P7465
Product Name :
AG-2 Protein, Human (HEK293, His, solution)
Product Type :
proteins
Host Species :
HEK293
Size :
10 μg;50 μg
List Price :
125;350 USD
list of Pubmed id :
405076099
Product Description :
AG-2 Protein, Human (HEK293, His, solution) is human recombinant AG-2 with a N-terminal His tag. AG-2 Protein, Human (HEK293, His) is expressed in HEK293 cells.
SpeciesSummary :
Human
Background :
AG-2 (Anterior gradient 2) is a human ortholog of the Xenopus laevis cement gland protein and a member of the protein disulfide isomerase (PDI) family. AG-2 is highly expressed and secreted in malignant cancer types, including breast carcinomas, pancreatic cancer, glioblastoma, prostate cancer and metastatic colorectal cancer. AGR2 is also a pro-oncogenic protein that stimulates EGFR ligand amphiregulin, regulate p53 signaling, and interact with the AAA+ protein Reptin. Overexpressed AG-2 stabilizes HIF-1α in tumor cells [1] [2] .
ALTnames :
rHuAG-2, His; HPC8; AGR2; AG2
Purity :
Greater than 95% as determined by reducing SDS-PAGE.
Buffer :
Supplied as a 0.2 μm filter solution of 20 mM Tris, 200 mM NaCl, 10% Glycerol, pH 8.0.
Storage :
Shipping with dry ice.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA