protein

Periostin Protein, Human (781a.a, HEK293, His)

HY-P74638

10 μg;50 μg;100 μg

85;240;380 USD

Periostin Protein, Human (781a.a, HEK293, His)

proteins

HEK293

10 μg;50 μg;100 μg

85;240;380 USD

Periostin (POSTN) is a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. POSTN binds to integrins and BMP1 to support cell adhesion, cell migration and the structural integrity of connective tissues. Periostin Protein, Human (781a.a, HEK293, His) is the recombinant human-derived Periostin protein, expressed by HEK293 , with C-His labeled tag. The total length of Periostin Protein, Human (781a.a, HEK293, His) is 781 a.a., with molecular weight of 66-80 kDa.

Human

Periostin (POSTN) is a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. POSTN binds to integrins to support adhesion and migration of epithelial cells, POSTN also enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase, contributing to the structural integrity of connective tissues. POSTN plays a role in cancer stem cell maintenance and metastasis. Lacking of POSTN causes cardiac valve disease, skeletal and dental defects [1] [2] .

Osteoblast-specific factor 2; OSF-2; POSTN; Periostin

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.0.

Shipping with dry ice