protein

PIG3 Protein, Human (His)

HY-P74632

5 μg;10 μg;50 μg;100 μg

50;85;240;400 USD

PIG3 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

50;85;240;400 USD

PIG3 is a key player in cellular processes, functioning as an enzyme that catalyzes NADPH-dependent quinone reduction. It exhibits moderate enzymatic activity towards β-naphthoquinone, with the para -quinone isomer (1,2-β-naphthoquinone) compared to the para -isomer (1,4-β-naphthoquinone). Obvious preference. PIG3 Protein, Human (His) is the recombinant human-derived PIG3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of PIG3 Protein, Human (His) is 332 a.a., with molecular weight of ~37.5 kDa.

Human

PIG3, or p53-induced gene 3, is a protein that catalyzes the NADPH-dependent reduction of quinones, showcasing a preference for the ortho-quinone isomer (1,2-beta-naphthoquinone) over the para isomer (1,4-beta-naphthoquinone). Additionally, PIG3 exhibits low enzymatic activity with beta-naphthoquinones and displays reductase activity for non-quinone compounds such as diamine and 2,6-dichloroindophenol in vitro. Beyond its enzymatic functions, PIG3 is involved in the generation of reactive oxygen species (ROS). This multifaceted role suggests that PIG3 may contribute to redox homeostasis by participating in quinone reduction and other reductase activities, while also being implicated in ROS production, highlighting its potential impact on cellular oxidative stress responses.

Quinone oxidoreductase PIG3; TP53I3; PIG3

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of sterile 50mM Tris-HCL, 300mM NaCl, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween 80.

Room temperature in continental US; may vary elsewhere.