protein

Adiponectin/Acrp30 Protein, Mouse (HEK293, His)

HY-P7461

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg

35;60;165;280;650;1150 USD

Adiponectin/Acrp30 Protein, Mouse (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;250 μg;500 μg

35;60;165;280;650;1150 USD

406167987

Adiponectin/Acrp30 Protein, Mouse (HEK293, His) is the most abundant peptide secreted by adipocytes, whose reduction plays a central role in obesity-related diseases, including insulin resistance/type 2 diabetes and cardiovascular disease [1] .

Mouse

Adiponectin has direct actions in liver, skeletal muscle, and the vasculature.Adiponectin exists in the circulation as varying molecular weight forms, produced by multimerization. Several endoplasmic reticulum ER-associated proteins, including ER oxidoreductase 1-α (Ero1-α), ER resident protein 44 (ERp44), disulfide-bond A oxidoreductase-like protein (DsbA-L), and glucose-regulated protein 94 (GPR94), have recently been found to be involved in the assembly and secretion of higher-order adiponectin complexes. Adiponectin administration in humans and rodents has insulin-sensitizing, anti-atherogenic, and anti-inflammatory effects, and, in certain settings, also decreases body weight [1] .

rMuAdiponectin, His; Acrp30; ADIPOQ

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.