protein

RGS5 Protein, Human (His)

HY-P74596

5 μg;10 μg;50 μg;100 μg

50;85;238;405 USD

RGS5 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

50;85;238;405 USD

RGS5, an adept signal transduction modulator, enhances G protein alpha subunit GTPase activity, promoting their transition to the inactive GDP-bound state. Interacting with G(i)-alpha and G(o)-alpha, it selectively excludes G(s)-alpha, highlighting its precise role in regulating specific G protein subunits and fine-tuning cellular signaling pathways. RGS5 Protein, Human (His) is the recombinant human-derived RGS5 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RGS5 Protein, Human (His) is 181 a.a., with molecular weight of ~25 kDa.

Human

RGS5, a proficient modulator of signal transduction, exerts its inhibitory impact by enhancing the GTPase activity of G protein alpha subunits, facilitating their transition into the inactive GDP-bound state. While it forms associations with G(i)-alpha and G(o)-alpha, its interaction excludes G(s)-alpha. This selective binding underscores its role in precisely regulating the activity of specific G protein subunits, contributing to the fine-tuning of cellular signaling pathways.

Regulator of G-protein signaling 5; RGS5

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from sterile 50 mM Tris-HCL, 300 mM NaCl, pH 7.4

Room temperature in continental US; may vary elsewhere.