protein

SARS-CoV Plpro/papain-like protease Protein (His)

HY-P74581

5 μg;10 μg;50 μg;100 μg

72;122;341;580 USD

SARS-CoV Plpro/papain-like protease Protein (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

72;122;341;580 USD

SARS CoV ORF1ab polyprotein (PP1ab) is a 7073 residues long polyprotein which further produces 5 non-structural proteins (NSPs) after processing through virally encoded proteases (NSP12-NSP16).All these 5 proteins are mainly involved in viral replication, assembly, and immune response modulation.SARS-CoV Plpro/papain-like protease Protein (His) is the recombinant Virus-derived SARS-CoV Plpro/papain-like protease protein, expressed by E.coli , with C-His labeled tag.

Virus

SARS CoV ORF1ab polyprotein (PP1ab) is a 7073 residues long polyprotein which further produces 5 non-structural proteins (NSPs) after processing through virally encoded proteases (NSP12-NSP16). All these 5 proteins are mainly involved in viral replication, assembly, and immune response modulation. Polyprotein degradation is mediated by main protease (Mpro) and papain-like protease (PLpro), PP1ab is thus processed into the individual NSPs that form the viral replication and transcription complex, The function of viral RNA transcription and replication is performed by a specific RNA dependent RNA polymerase (RdRp) region present in PP1ab [1] [2] .

SARS-CoV (strain WH20) Plpro / papain-like protease

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as 0.22 μm filtered solution in 50 mM Tris, 0.1% Tween, 150 mM NaCl, pH 9.0.

Shipping with dry ice