protein

SFRP4 Protein, Mouse (HEK293, His)

HY-P74550

5 μg;10 μg;50 μg

65;105;290 USD

SFRP4 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

65;105;290 USD

SFRP4 Protein, a soluble frizzled-related protein, directly interacts with Wnts, modulating Wnt signaling. It regulates cell growth and differentiation, impacting bone morphogenesis. In the adult uterus, SFRP4 serves as a regulator, potentially increasing apoptosis during ovulation via FZ1/FZ4/WNT4 signaling modulation. Additionally, it exhibits phosphaturic effects by inhibiting sodium-dependent phosphate uptake specifically. SFRP4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SFRP4 protein, expressed by HEK293 , with C-His labeled tag.

Mouse

SFRP4 is a soluble frizzled-related protein that acts as a modulator of Wnt signaling by directly interacting with Wnts. It regulates cell growth and differentiation in specific cell types and plays a role in bone morphogenesis. Additionally, SFRP4 acts as a regulator of adult uterine morphology and function and may increase apoptosis during ovulation, potentially through modulation of FZ1/FZ4/WNT4 signaling. It also exhibits phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.

Secreted frizzled-related protein 4; sFRP-4; FrpHE; FRPHE

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.