protein

TCL1A Protein, Human (His)

HY-P74530

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;60;165;280;850;1300 USD

TCL1A Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;60;165;280;850;1300 USD

TCL1A protein plays a crucial role in cell signaling by actively enhancing the phosphorylation and activation of AKT1, AKT2, and AKT3 while promoting the nuclear translocation of AKT1. Additionally, it aids cell proliferation, stabilizes mitochondrial membrane potential, and promotes cell survival. TCL1A Protein, Human (His) is the recombinant human-derived TCL1A protein, expressed by E. coli , with N-His labeled tag. The total length of TCL1A Protein, Human (His) is 113 a.a., with molecular weight of ~14 kDa.

Human

The T-cell leukemia/lymphoma protein 1A (TCL1A) is a multifaceted regulator that plays a pivotal role in cellular processes. It functions by enhancing the phosphorylation and activation of AKT1, AKT2, and AKT3, leading to their nuclear translocation. Additionally, TCL1A promotes cell proliferation, stabilizes mitochondrial membrane potential, and supports cell survival. Existing as a homodimer, TCL1A interacts with AKT1, AKT2, and AKT3 through their pleckstrin homology (PH) domain. Notably, TCL1A forms a complex with PNPT1, but this interaction does not affect PNPT1 exonuclease activity. The diverse molecular interactions and functional implications of TCL1A underscore its significance in cellular signaling pathways and contribute to our understanding of its role in cell growth and survival (

T-cell leukemia/lymphoma protein 1A; Oncogene TCL-1; TCL1A; TCL1

Greater than 88% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.