protein

VEGFR-2 Protein, Rat (HEK293, His)

HY-P74470

2 μg;10 μg;50 μg;100 μg;500 μg

35;100;280;480;1330 USD

VEGFR-2 Protein, Rat (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg

35;100;280;480;1330 USD

VEGFR-2 Protein is a type III receptor tyrosine kinase, also known as the receptor for vascular endothelial growth factor 2. VEGFR-2 Protein mediates vascular endothelial growth factor (VEGF)-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting, and plays a key role in angiogenesis and vasculogenesis. VEGFR-2 Protein, Rat (HEK293, His) is the recombinant rat-derived VEGFR-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of VEGFR-2 Protein, Rat (HEK293, His) is 741 a.a., with molecular weight of ~115-180 kDa.

Rat

VEGFR-2 protein mediates vascular endothelial growth factor (VEGF)-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting, and plays a key role in angiogenesis and vasculogenesis [1] [3] . The signal of VEGFR-2 protein is a survival mechanism in hippocampal neurons, which can prevent mitochondrial dysfunction and oxidative stress [2] . VEGFR-2 Protein is highly expressed in the microvessels of diabetes and can be used as a biomarker for early diagnosis of diabetes retinopathy (DR) [4] . VEGFR-2 protein mediates hydrogen sulfide (H 2 S)-induced dilation of rat basilar artery [5] .

Vascular endothelial growth factor receptor 2; VEGFR-2; FLK-1; CD309

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.