protein

ACE2 Protein, Mouse (HEK293, His)

HY-P74434

5 μg;10 μg;50 μg;100 μg

78;132;370;630 USD

ACE2 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

78;132;370;630 USD

Mouse

Angiotensin-converting enzyme 2 (ACE2), a metallopeptidase, is the functional receptor for SARS-CoV. ACE2 can be immunoprecipitated by the S1 domain of the SARS-CoV virus and that ACE2 can promote viral replication. ACE2 is abundantly present in humans in the epithelia of lung and small intestine, which might provide possible routes of entry for the SARS-CoV. ACE2, previously identified as the cellular receptor for SARS-CoV, also acts as a receptor of the new coronavirus (SARS-CoV-2). ACE2 is also thought to be an essential regulator of cardiac function and blood pressure control, possibly by acting as a natural counterpart of ACE1 [1] [2] .

Angiotensin-converting enzyme 2; ACE-2; ACEH; ACE-related carboxypeptidase

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 25 mM Tris-HCL, 150 mM NaCl, 1 mM ZnCl2, pH 7.4 or PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.