protein

Aconitase 2/ACO2 Protein, Human (sf9, His-GST)

HY-P74432

5 μg;10 μg;50 μg;100 μg

70;115;300;510 USD

Aconitase 2/ACO2 Protein, Human (sf9, His-GST)

proteins

Sf9 insect cells

5 μg;10 μg;50 μg;100 μg

70;115;300;510 USD

Aconitase 2/ACO2 Protein, an enzyme, plays a vital role in the tricarboxylic acid cycle and energy production. Dysregulation of Aconitase 2/ACO2 Protein has been associated with mitochondrial dysfunction and oxidative stress. Targeting Aconitase 2/ACO2 Protein may provide potential therapeutic strategies by regulating energy metabolism, reducing oxidative damage, and improving mitochondrial function. Aconitase 2/ACO2 Protein, Human (sf9, His-GST) is the recombinant human-derived Aconitase 2/ACO2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of Aconitase 2/ACO2 Protein, Human (sf9, His-GST) is 753 a.a., with molecular weight of ~110 kDa.

Human

The Aconitase 2/ACO2 protein emerges as a pivotal catalyst in cellular processes, facilitating the isomerization of citrate to isocitrate through the intermediate cis-aconitate. This enzymatic activity is instrumental in key metabolic pathways, contributing to the dynamic regulation of citric acid cycle intermediates. The ACO2 protein's role in orchestrating the conversion of citrate to isocitrate underscores its significance in maintaining cellular energy balance and metabolic homeostasis.

Aconitate hydratase; Aconitase; ACO2

Greater than 90% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 500 mM NaCl, 10% Glycerol, 0.5 mM TCEP, pH 8.0, 0.5 mM GSH.

Shipping with dry ice