protein

C2/Complement C2 Protein, Mouse (HEK293, His)

HY-P74374

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

55;85;240;385;1080;1720 USD

C2/Complement C2 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

55;85;240;385;1080;1720 USD

Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1, resulting in the formation of two distinct fragments: C2b and C2a. The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b, leading to the formation of C3 or C5 convertase. C2/Complement C2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived C2/Complement C2 protein, expressed by HEK293 , with C-His labeled tag.

Mouse

Complement C2, a vital component of the classical pathway within the complement system, undergoes cleavage by activated factor C1 into two fragments: C2b and C2a. The generated C2a fragment, possessing serine protease activity, subsequently associates with complement factor C4b, culminating in the formation of the C3 or C5 convertase. This enzymatic complex plays a pivotal role in the activation cascade of the complement system, facilitating the downstream proteolytic cleavage of complement factors C3 and C5, which are integral steps in the immune response. The orchestrated interplay of C2 in the classical pathway underscores its significance in mediating immune defense mechanisms and maintaining immune homeostasis. (

Complement C2; C3/C5 convertase; C2

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.