protein

Cadherin-1/CD324 Protein, Human (HEK293, Fc)

HY-P74370

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;60;155;250;750;1200 USD

Cadherin-1/CD324 Protein, Human (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;60;155;250;750;1200 USD

The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag.

Human

Cadherin-1 (CD324) is a calcium-dependent cell adhesion protein known for its preference to interact homophilically with itself in adjacent cells, thereby contributing to the sorting of heterogeneous cell types. CDH1, a member of the cadherin family, plays a crucial role in regulating cell-cell adhesions, influencing the mobility and proliferation of epithelial cells. Notably, CDH1 exhibits a potent role as an invasive suppressor and serves as a ligand for integrin alpha-E/beta-7E, impacting non-amyloidogenic degradation of Abeta precursors. Moreover, CDH1 demonstrates a robust inhibitory effect on the production of APP C99 and C83, further emphasizing its multifaceted involvement in cellular processes and its potential implications in pathological contexts.

Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.