protein

Nucleocapsid Protein (His)

HY-P7437

10 μg;50 μg

55;165 USD

Nucleocapsid Protein (His)

proteins

E. coli

10 μg;50 μg

55;165 USD

405021307

Nucleocapsid Protein (His) expressed by E. coli systems. Nucleocapsid Protein is required for coronavirus RNA synthesis and has RNA chaperone activity [1] .

Virus

Coronaviruses are enveloped viruses with a positive-sense RNA genomeand and has a nucleocapsid of helical symmetry. The Nucleocapsid Protein localize to the cytoplasm and the nucleolus in both virus-infected primary cells and in cells transfected with plasmids that express N protein [1] . Nucleocapsid Protein is a basic protein and is abundant in coronaviruses, which has nonspecific binding activity toward nucleic acids, including ssRNA, ssDNA, and dsDNA. Nucleocapsid Protein is an essential RNA-binding viral protein in human coronavirus (CoV)-infected cells, is required for the replication and transcription of viral RNA. Human CoV NP is a valid target for antiviral drug research [1] [2] .

2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 300 mM NaCl, 10% Glycerol, 1 mM EDTA, pH 8.0.

Shipping with dry ice.