protein

Cadherin-13 Protein, Rat (HEK293)

HY-P74364

5 μg;10 μg;50 μg

45;75;190 USD

Cadherin-13 Protein, Rat (HEK293)

proteins

HEK293

5 μg;10 μg;50 μg

45;75;190 USD

Cadherin-13 Protein is an atypical member of the cadherin family, devoid of a transmembrane domain and anchored to the exterior surface of the plasma membrane via a glycosylphosphatidylinositol anchor. And it exhibits a preference for homophilic interactions, fostering connections between neighboring cells and potentially playing a role in cell type sorting. Cadherin-13 may act as negative regulators of neural cell growth. Moreover, it may act rather as a signalling receptor participating in recognition of the environment and regulation of cell motility, proliferation and phenotype. Cadherin-13 Protein, Rat (HEK293) is the recombinant rat-derived Cadherin-13 protein, expressed by HEK293 , with tag free.

Rat

Cadherin-13 is an atypical member of the cadherin family, devoid of a transmembrane domain and anchored to the exterior surface of the plasma membrane via a glycosylphosphatidylinositol anchor. And it exhibits a preference for homophilic interactions, fostering connections between neighboring cells and potentially playing a role in cell type sorting. Cadherin-13 may act as negative regulators of neural cell growth. Cadherin-13 is highly expressed in nervous and cardiovascular system (in endothelial and smooth muscle cells). Thereby, it may facilitate progression of proliferative vascular disorders such as atherosclerosis, restenosis and tumor angiogenesis. Moreover, it may act rather as a signalling receptor participating in recognition of the environment and regulation of cell motility, proliferation and phenotype. Cadherin-13-dependent activation of PI3K/Akt/GSK3β signalling axis protects endothelial cells from oxidative stress-induced apoptosis.

Cadherin-13; H-cadherin; T-cadherin; T-cad; CDH13

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.