protein

CD23/Fc epsilon RII Protein, Rat (HEK293, Fc)

HY-P74320

5 μg;10 μg

62;100 USD

CD23/Fc epsilon RII Protein, Rat (HEK293, Fc)

proteins

HEK293

5 μg;10 μg

62;100 USD

CD23, also known as Fc epsilon Receptor II (Fc epsilon RII), is a low-affinity receptor for immunoglobulin E (IgE) and complement receptor 2 (CR2/CD21). CD23 regulates IgE production and B-cell differentiation, aiding in IGE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is 282 a.a., with molecular weight of 60-75 kDa.

Rat

CD23, also known as Fc epsilon Receptor II (Fc epsilon RII), is a low-affinity receptor for immunoglobulin E (IgE) and complement receptor 2 (CR2/CD21). CD23 on B cells plays a crucial role in the regulation of IgE production and B cell differentiation, promoting the uptake and presentation of IGE-dependent antigens to T cells. In macrophages, IgE binding and antigenic crosslinking trigger the parasite's intracellular killing by activating the L-arginine-nitric oxide pathway. CD23 forms homologous trimers and interacts with IGHE, particularly through its C-type lectin domain, regulating IgE homeostasis. CD23 plays an important role in immune responses ranging from B-cell activation to macrophage-mediated parasite defense [1] [2] .

Low affinity immunoglobulin epsilon Fc receptor; BLAST-2; FCER2; CD23A

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, PH 7.4.

Room temperature in continental US; may vary elsewhere.