protein

SARS-CoV-2 3C-like Proteinase (N-His)

HY-P7429A

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

62;100;280;450;1250;2000 USD

SARS-CoV-2 3C-like Proteinase (N-His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

62;100;280;450;1250;2000 USD

SARS-CoV-2 3C-like Proteinase (His), His, expressed in E.coli, mediates viral polyprotein maturation and multiple cleavages of host proteins to modulate viral translation and transcription with a His tag at the N-terminus [1] .

Virus

The 3C protease has been regarded as a valid target due to its structural similarity among different picornaviruses and minimal sequence similarity with host proteins; therefore, the development of potent inhibitors against the 3C protease as an antiviral drug is ongoing. Duck hepatitis A virus (DHAV) belongs to the Picornavidea family and is a major threat to the poultry industry [1] .

M Proteinase; 3CL Proteinase; 2019-nCoV 3C-like Proteinase

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 10% trehalose, 0.02% Tween80.

Room temperature in continental US; may vary elsewhere.