TGFBR2/TGF-beta RII Protein, Mouse (HEK293, His) | MedChem Express LLC HY-P7428 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

TGFBR2/TGF-beta RII Protein, Mouse (HEK293, His)

catalog :

HY-P7428

quantity :

10 μg;50 μg

price :

80;220 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7428

Product Name :

TGFBR2/TGF-beta RII Protein, Mouse (HEK293, His)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

80;220 USD

list of Pubmed id :

405021299

Product Description :

TGFBR2/TGF-beta RII Protein, Mouse (HEK293, His), His consists of N-terminal ectodomain and C-terminal protein kinase domain with his tag.TGF-beta receptor type-2 is the ligand-binding receptor for all members of the TGF-β family.

SpeciesSummary :

Mouse

Background :

Transforming growth factor-beta (TGF-β) is a pleiotropic cytokine with the capability to act as tumor suppressor or tumor promoter depending on the cellular context. TGF-beta receptor type-2 (TGFBR2) is the ligand-binding receptor for all members of the TGF-βfamily and expressed in virtually all cell types including fibroblasts. Regulation of tumor-stromal cross-talk through fibroblastic TGF-βpathway may depend on fibroblast phenotype, emphasising the importance to characterise tumor microenvironment subtypes [1] .

ALTnames :

TGFR-2; TGF-beta type II receptor; TGF-beta receptor type 2; TbetaR-II

Purity :

Greater than 95% as determined by reducing SDS-PAGE

Buffer :

Lyophilized after extensive dialysis against PBS, pH 7.4.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage