protein

CD68 Protein, Mouse (sf9, His)

HY-P74278

50 μg

420 USD

CD68 Protein, Mouse (sf9, His)

proteins

Sf9 insect cells

50 μg

420 USD

The CD68 protein plays a crucial role in the phagocytic activity of tissue macrophages, affecting lysosomal metabolism and interactions with cells and pathogens. It binds to specific lectins or selectins and guides macrophages to migrate to specific sites. CD68 Protein, Mouse (sf9, His) is the recombinant mouse-derived CD68 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Mouse

The CD68 protein is implicated in potentially playing a crucial role in the phagocytic activities of tissue macrophages, influencing both intracellular lysosomal metabolism and extracellular interactions involving cell-cell and cell-pathogen encounters. It exhibits binding capabilities to tissue- and organ-specific lectins or selectins, facilitating the homing of distinct macrophage subsets to specific anatomical sites. The rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane suggests a dynamic mechanism that enables macrophages to navigate and traverse selectin-bearing substrates or interact with other cells. This multifaceted functionality of CD68 underscores its significance in the intricate processes of immune response and cellular interactions within diverse tissue microenvironments.

CD68 antigenmacrophage antigen CD68; CD68; Gp110; Macrosialin; SRD1

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0, 10% Glycerol. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.