protein

Coagulation Factor II/F2 Protein, Rat (HEK293, His)

HY-P74241

5 μg;10 μg;50 μg;100 μg

70;115;300;480 USD

Coagulation Factor II/F2 Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

70;115;300;480 USD

The factor II/F2 protein (also known as thrombin) plays a key role in blood homeostasis, inflammation, and wound healing. As a multifunctional enzyme, it catalyzes the conversion of fibrinogen into fibrin to form the coagulation network. Coagulation Factor II/F2 Protein, Rat (HEK293, His) is the recombinant rat-derived Coagulation Factor II/F2 protein, expressed by HEK293 , with C-His labeled tag.

Rat

Coagulation Factor II/F2 Protein, commonly known as thrombin, plays a pivotal role in blood homeostasis, inflammation, and wound healing. This multifunctional enzyme, with its ability to cleave bonds after Arg and Lys, serves as a key player in the coagulation cascade. Thrombin catalyzes the conversion of fibrinogen to fibrin, forming the essential meshwork for blood clotting. Additionally, it activates several factors including V, VII, VIII, XIII, and, when in complex with thrombomodulin, protein C, contributing to the intricate regulation of coagulation and anticoagulation pathways. The diverse functions of Coagulation Factor II/F2 underscore its indispensable role in maintaining the delicate balance of blood clotting, immune responses, and the intricate processes involved in tissue repair and healing.

Prothrombin; Coagulation factor II

Greater than 90% as determined by Tris-Bis PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.