protein

Coagulation Factor XIV/PROC Protein, Human (HEK293, His)

HY-P74237

10 μg;20 μg;50 μg;100 μg

85;140;265;425 USD

Coagulation Factor XIV/PROC Protein, Human (HEK293, His)

proteins

HEK293

10 μg;20 μg;50 μg;100 μg

85;140;265;425 USD

Coagulation Factor XIV/PROC is a vital vitamin K-dependent serine protease regulating blood coagulation. Active Protein C inactivates factors Va and VIIIa in the presence of calcium ions and phospholipids, maintaining the intricate balance of coagulation pathways. Its protective effect on endothelial cell barrier function underscores a broader impact on vascular integrity. Coagulation Factor XIV/PROC Protein, Human (HEK293, His) is the recombinant human-derived Coagulation Factor XIV/PROC protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor XIV/PROC Protein, Human (HEK293, His) is 443 a.a., with molecular weight of 56-64 & 45 kDa, respectively.

Human

Coagulation Factor XIV (PROC) is a vitamin K-dependent serine protease crucial for the regulation of blood coagulation. In its active form, Protein C plays a vital role in inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids, contributing significantly to the intricate balance of coagulation pathways. Additionally, Protein C demonstrates a protective effect on endothelial cell barrier function, highlighting its broader impact on vascular integrity.

Vitamin K-dependent protein C; APC; Protein C; PROC

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.