protein

VEGF121 Protein, Human (120 a.a)

HY-P7420

2 μg;10 μg;50 μg;100 μg

56;140;350;560 USD

VEGF121 Protein, Human (120 a.a)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

56;140;350;560 USD

384647088

VEGF121 Protein, Human (120 a.a), a VEGF isoform splice variant, cannot bind to heparin. VEGF121 Protein is predictor for survival in activated B-cell-like diffuse large B-cell lymphoma and is related to an immune response gene signature conserved in cancers.

Human

VEGF-121 lacks heparin binding ability and requires cell-surface heparan sulfates for efficient binding to the VEGF receptors of human melanoma cells [1] . In addition, VEGF-121 and VEGF 165 regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model. VEGF-121 is predictor for survival in activated B-cell-like diffuse large B-cell lymphoma and is related to an immune response gene signature conserved in cancers [2] [3] . Furthermore, VEGF-121 plasma level is biomarker for response to anti-angiogenetic therapy in recurrent glioblastoma [4] .

VEGF-AA; rHuVEGF-121; VPF

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.