product summary
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company name :
MedChem Express LLC
product type :
protein
product name :
Vaspin Protein, Human
catalog :
HY-P7419
quantity :
2 μg;10 μg
price :
40;110 USD
product information
Catalog Number :
HY-P7419
Product Name :
Vaspin Protein, Human
Product Type :
proteins
Host Species :
E. coli
Size :
2 μg;10 μg
List Price :
40;110 USD
list of Pubmed id :
384647087
Product Description :
Vaspin Protein, Human, as a secretory adipokine, exerts a protective role on insulin resistance.
SpeciesSummary :
Human
Background :
Vaspin is a beneficial adipokine counteracting insulin-resistance and inflammatory processes in obese mice. vaspin can alleviate ischaemia/reperfusion (I/R) injury in the heart by suppressing myocardial apoptosis through AMPK-mTOR-dependent activation of autophagic flux, and then provided a potential breakthrough in the treatment of myocardial I/R injury and other ischaemic diseases [1] [2] . In addition, vaspin induces activation of the PI3K/AKT axis, independent of insulin receptor activation, promotes GLUT4 expression and translocation and sensitises older obese human skeletal muscle to insulin-mediated glucose uptake [3] .
ALTnames :
rHuVaspin; Serpin A12; OL-64
Purity :
Greater than 95% as determined by reducing SDS-PAGE
Buffer :
Lyophilized from a 0.2 μm filtered solution of PBS or 20 mM PB, 150 mM NaCl, pH 7.4.
Storage :
Room temperature in continental US; may vary elsewhere.
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com
609-228-6898
headquarters: USA