protein

EGFR Protein, Human (621a.a, HEK293, Fc)

HY-P74177

5 μg;10 μg;20 μg;50 μg;100 μg

40;60;95;165;250 USD

EGFR Protein, Human (621a.a, HEK293, Fc)

Protein

HEK293

5 μg;10 μg;20 μg;50 μg;100 μg

40;60;95;165;250 USD

The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (621a.a, HEK293, Fc) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-hFc labeled tag.