protein

TNF-alpha/TNFSF2 Protein, Mouse (His)

HY-P7417

2 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

TNF-alpha/TNFSF2 Protein, Mouse (His)

proteins

E. coli

2 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

384647085

TNF-alpha/TNFSF2 Protein, Mouse (His) is recombinant mouse tumor necrosis factor alpha (TNF-α) with his tag.TNF-alpha/TNFSF2 Protein, a major mediator of inflammation, is involved in a number of infectious and parasitic diseases.

Mouse

Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine produced by a wide variety of cell types of mostly hematopoietic, but also of nonhematopoietic, origin. TNFα is instrumental in the immune elimination of various infectious agents such as Candida albicans, Listeria monocytogenes, or mycobacteria and exerts potent proinflammatory effects, e.g. by inducing the expression of adhesion molecules such as VCAM-1, intercellular adhesion molecule 1 (ICAM-1), or E-selectin on endothelial cells and other cell types [1] [2] .

rMuTNF-α, His; Cachectin; TNFSF2

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against PBS or 20 mM PB, 150 mM NaCl, pH 7.4 or 50 mM Tris-HCL, 300 mM NaCl, pH 7.4, 5% trehalose,5% mannitol and 0.01% Tween80.

Room temperature in continental US; may vary elsewhere.