protein

E-Selectin/CD62E Protein, Human (HEK293, His-Fc)

HY-P74161

5 μg;10 μg;50 μg;100 μg

35;50;130;220 USD

E-Selectin/CD62E Protein, Human (HEK293, His-Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

35;50;130;220 USD

E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-Selectin/CD62E Protein, Human (HEK293, His-Fc) is the recombinant human-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of E-Selectin/CD62E Protein, Human (HEK293, His-Fc) is 535 a.a., with molecular weight of 140-150 kDa.

Human

E-selectin/CD62E Protein is a cell-surface glycoprotein that plays a crucial role in immunoadhesion. It mediates the adhesion of blood neutrophils in cytokine-activated endothelium by interacting with SELPLG/PSGL1. Additionally, E-selectin/CD62E Protein may be involved in capillary morphogenesis. It interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, and it is worth noting that SELPLG sulfation is not necessary for this interaction.

E-selectin; ELAM-1; LECAM2; CD62E; SELE

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.