TIM-3/HAVCR2 Protein, Human (HEK293, Fc) | MedChem Express LLC HY-P7415 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

TIM-3/HAVCR2 Protein, Human (HEK293, Fc)

catalog :

HY-P7415

quantity :

10 μg;50 μg

price :

115;320 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7415

Product Name :

TIM-3/HAVCR2 Protein, Human (HEK293, Fc)

Product Type :

proteins

Host Species :

HEK293

Size :

10 μg;50 μg

List Price :

115;320 USD

list of Pubmed id :

405076083

Product Description :

TIM3 Protein, Human (HEK293, Fc) is a type I transmembrane glycoprotein belonging to T Cell Immunoglobulin Mucin (TIM) family, and is involved in regulating innate and adaptive immunity.

SpeciesSummary :

Human

Background :

T Cell Immunoglobulin Mucin 3 (TIM-3), also known as Hepatitis A virus cellular receptor 2 (HAVCR2), is an immunomodulatory molecule and upregulated in T cells by several cytokines. TIM-3 also influences mast cell function but its transcriptional regulation in mast cells has not been clarified. Human TIM-3 consists of a membrane distal variable immunoglobulin (IgV)-like domain involved in ligand interactions, a membrane proximal mucin domain and a transmembrane domain that is connected to an intracellular cytoplasmic tail involved in phosphotyrosine-dependent signaling [1] [2] [3] .

ALTnames :

rHuTIM-3, Fc Chimera; TIMD-3; CD366; HAVCR2

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage