protein

Galectin-1/LGALS1 Protein, Rat

HY-P74130

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

Galectin-1/LGALS1 Protein, Rat

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

Galectin-1/LGALS1 protein is a β-galactoside-binding lectin that regulates apoptosis, cell proliferation and differentiation by inhibiting CD45 protein phosphatase activity and preventing Lyn kinase dephosphorylation. As a homodimer, it induces T cell apoptosis and interacts with CD2, CD3, CD4, CD6, CD7, CD43, ALCAM, CD45, laminin, and SUSD2. Galectin-1/LGALS1 Protein, Rat is the recombinant rat-derived Galectin-1/LGALS1 protein, expressed by E. coli , with tag free. The total length of Galectin-1/LGALS1 Protein, Rat is 134 a.a., with molecular weight of ~13 kDa.

Rat

Galectin-1/LGALS1 Protein is a lectin with a high affinity for binding beta-galactoside and a diverse range of complex carbohydrates. This protein serves a crucial role in the regulation of apoptosis, cell proliferation, and cell differentiation. Notably, it inhibits the activity of CD45 protein phosphatase, leading to the prevention of Lyn kinase dephosphorylation. Galectin-1/LGALS1 is a potent inducer of T-cell apoptosis. Existing as a homodimer, it forms interactions with various proteins, including CD2, CD3, CD4, CD6, CD7, CD43, ALCAM, and CD45. Additionally, Galectin-1/LGALS1 interacts with laminin through poly-N-acetyllactosamine binding and associates with SUSD2. Furthermore, it engages in a notable interaction with the cargo receptor TMED10, facilitating translocation from the cytoplasm into the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and subsequent secretion.

Galectin-1; Gal-1; HLBP14; Galaptin; HBL; LGALS1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.