TGF alpha/TGFA Protein, Human | MedChem Express LLC HY-P7411 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

TGF alpha/TGFA Protein, Human

catalog :

HY-P7411

quantity :

10 μg;50 μg

price :

70;160 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7411

Product Name :

TGF alpha/TGFA Protein, Human

Product Type :

proteins

Host Species :

E. coli

Size :

10 μg;50 μg

List Price :

70;160 USD

list of Pubmed id :

384647080

Product Description :

TGF-alpha Protein, Human is a 50-amino-acid polypeptide that binds to the epidermal growth factor (EGF) receptor and stimulates cell growth.

SpeciesSummary :

Human

Background :

Transforming growth factor alpha (TGF-α) is a principal molecule in the normal and neoplastic development of the mammary gland. Binding of TGF-α to the epidermal growth factor receptor (EGFR), activates the EGFRs' endogenous tyrosine kinase activity and stimulates growth of the epithelium in the virgin and pregnant mouse mammary gland. TGF-α expression can be detected in breast cancer cells in vivo and in vitro and overexpression can elicit partial transformation or immortalized human and rodent mammary epithelial cells [1] [2] .

ALTnames :

rHuTGF-α; ETGF; TGF-type I

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against PBS.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage