protein

SHH Protein, Human (C24IVI)

HY-P7408

2 μg;10 μg;50 μg;100 μg

35;85;240;400 USD

SHH Protein, Human (C24IVI)

Protein

E. coli

2 μg;10 μg;50 μg;100 μg

35;85;240;400 USD

Sonic Hedgehog (SHH) Protein is a secretory glycoprotein of the Hedgehog family that can self-cleave to form N-SHH. SHH Protein activates Smo by binding to Frizzled and LRP6, inhibits GSK-3β to stabilize β-catenin, and activates FOXM1. SHH Protein also promotes NO release and shortens myocardial APD by phosphorylating eNOS through PI3K/Akt. SHH Protein can promote the maturation of sweat gland cells in three-dimensional culture and play a cardioprotective role in the pig ischemia-reperfusion model. SHH Protein, Human (C24IVI) is a recombinant human SHH protein expressed in E. coli with C24IVI-mutation and tag-free.