protein

IgG1 Protein, Mouse (HEK293, C102S)

HY-P73901

20 μg;50 μg;100 μg

80;150;238 USD

IgG1 Protein, Mouse (HEK293, C102S)

proteins

HEK293

20 μg;50 μg;100 μg

80;150;238 USD

IgG1 Protein is the most abundant Immunoglobulin G (IgG) subclass in human sera and is important for mediating antibody responses against viral pathogens. IgG1 enables antigen binding activity and immunoglobulin receptor binding activity. It acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity, phagocytosis, and positive regulation of immune response. IgG1 Protein, Mouse (HEK293, C102S) is the recombinant mouse-derived IgG1 protein, expressed by HEK293 , with tag free.

Mouse

Ig gamma-1 chain C region secreted form (IgG1) is the most abundant Immunoglobulin G (IgG) subclass in human sera and is important for mediating antibody responses against viral pathogens. It does so by binding to soluble proteins and membrane protein antigens via its variable domain and concomitantly activating effector mechanisms of the innate immune system. IgG1 enables antigen binding activity and immunoglobulin receptor binding activity. It acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity, phagocytosis, and positive regulation of immune response. IgG1 can effectively bind to C1q causing complement-dependent cytotoxicity (CDC) and can bind to each of the different Fc receptors resulting in antibody-dependent cell-mediated cytotoxicity (ADCC) [1] .

Immunoglobulin heavy constant gamma 1; IGHG1

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Shipping with dry ice