protein

IL-23 alpha & IL-12 beta Heterodimer Protein, Rabbit (HEK293, His)

HY-P73887

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

48;135;380;650;1400;2100 USD

IL-23 alpha & IL-12 beta Heterodimer Protein, Rabbit (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

48;135;380;650;1400;2100 USD

IL-23 alpha protein is part of the IL-6 superfamily and contains IL-23 alpha and IL-12 beta subunits that form a biologically active complex. It has a crucial impact on the differentiation and activation of Th17 cells associated with autoimmune diseases. IL-23 Protein, Rabbit (HEK293, His) is a recombinant protein dimer complex containing Rabbit-derived IL-23 alpha & IL-12 beta Heterodimer protein, expressed by HEK293 , with C-His labeled tag.

Rabbit

The IL-23 alpha protein belongs to the IL-6 superfamily, a group of cytokines with diverse functions in immune regulation and inflammation. This heterodimeric protein is composed of two subunits, IL-23 alpha and IL-12 beta, which combine to form a biologically active complex. IL-23 alpha plays a crucial role in the differentiation and activation of T-helper 17 (Th17) cells, a subset of CD4+ T cells involved in the pathogenesis of autoimmune diseases and chronic inflammation. It stimulates the production of pro-inflammatory cytokines, such as IL-17 and IL-22, and promotes tissue inflammation and immune cell recruitment. Dysregulation of IL-23 alpha has been implicated in various autoimmune diseases, making it an attractive target for therapeutic interventions aimed at modulating immune responses and controlling inflammation.

IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.