protein

IL-32 alpha Protein, Human (HEK293, His)

HY-P73884

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

32;80;200;300;1050;1800 USD

IL-32 alpha Protein, Human (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

32;80;200;300;1050;1800 USD

IL-32 protein is a member of the cytokine family whose expression increases following T cell activation or IL-2-induced NK cell activation. It plays a key role in inducing macrophages to produce TNFα, which contributes to the inflammatory response. IL-32 alphaProtein, Human (HEK293, His) is the recombinant human-derived IL-32 alpha protein, expressed by HEK293 , with C-His labeled tag.

Human

IL-32 Protein, a member of the cytokine family, is characterized by features such as a tyrosine sulfation site, three potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Its expression is notably increased following the activation of T-cells by mitogens or the activation of NK cells by IL-2. IL-32 plays a pivotal role in inducing the production of TNFalpha from macrophage cells, implicating its involvement in inflammatory responses. The gene exhibits alternative transcriptional splice variants, giving rise to different isoforms with distinct functional characteristics. IL-32 demonstrates broad expression across various tissues, with substantial levels observed in the small intestine (RPKM 122.1), spleen (RPKM 121.0), and 22 other tissues, underscoring its diverse roles and potential contributions to immune modulation and tissue-specific functions.

Interleukin-32; IL-32; NK4; TAIF; IL-32 alpha

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalos.

Room temperature in continental US; may vary elsewhere.