protein

Prolactin R Protein, Human (HEK293, His)

HY-P73696

10 μg;50 μg;100 μg;500 μg;1 mg

65;180;300;840;1450 USD

Prolactin R Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg;100 μg;500 μg;1 mg

65;180;300;840;1450 USD

The prolactin R protein is the receptor for prolactin, encoded by this gene, and promotes prolactin-dependent signaling through ligand-induced dimerization. This gene exhibits multiple splice variants, encodes multiple isoforms, and has a potential role in regulating the endocrine and autocrine effects of prolactin. Prolactin R Protein, Human (HEK293, His) is the recombinant human-derived Prolactin R protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Prolactin R Protein, Human (HEK293, His) is 210 a.a.

Human

Prolactin R Protein, encoded by this gene, is a receptor for the anterior pituitary hormone prolactin and is a member of the type I cytokine receptor family. Its function involves prolactin-dependent signaling, triggered by ligand-induced dimerization of the prolactin receptor. The gene exhibits several alternatively spliced transcript variants encoding diverse membrane-bound and soluble isoforms, potentially contributing to the modulation of the endocrine and autocrine effects of prolactin in both normal tissue and cancer. The expression of Prolactin R demonstrates bias, with notable levels observed in the placenta (RPKM 18.9), endometrium (RPKM 11.6), and eight other tissues, underscoring its specialized role in various physiological contexts and its potential involvement in reproductive and endocrine processes.

Prolactin receptor; PRL-R; Prolactin R

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, 5-8% Trehalose, 0.01% Tween 80, pH 7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.