protein

Shiga toxin 2B Protein, E. coli (His)

HY-P73650

50 μg

560 USD

Shiga toxin 2B Protein, E. coli (His)

proteins

E. coli

50 μg

560 USD

Shiga toxin 2B Proteinas, specifically its B subunit, binds the holotoxin to target cell receptors, such as globotriaosylceramide (Gb3) on human intestinal microvilli. Its capability to recognize and engage with these receptors underscores its pivotal role in initiating the holotoxin's interaction with the target cell surface, setting the stage for subsequent cellular responses and internalization processes. Shiga toxin 2B Protein, E. coli (His) is the recombinant E. coli-derived Shiga toxin 2B protein, expressed by E. coli , with N-His labeled tag. The total length of Shiga toxin 2B Protein, E. coli (His) is 89 a.a., with molecular weight of ~16 kDa.

E.coli

The Shiga toxin 2B protein, specifically its B subunit, assumes the critical role of binding the holotoxin to specific receptors on the surface of target cells. Notably, this binding interaction is directed towards receptors such as globotriaosylceramide (Gb3), particularly located on human intestinal microvilli. The B subunit's capability to recognize and engage with these specific receptors underscores its pivotal function in facilitating the initial stages of the holotoxin's interaction with the target cell surface, setting the stage for subsequent cellular responses and internalization processes.

Shiga toxin 2 B subunit; Stx2 holotoxin B subunit; stx2B; stx2dB

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.