protein

SSB Protein, Human

HY-P73630A

5 μg;10 μg;50 μg;100 μg;500 μg

68;115;300;510;1425 USD

SSB Protein, Human

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg

68;115;300;510;1425 USD

The SSB protein critically binds to the 3' poly(U) terminus of RNA polymerase III transcripts, preventing exonuclease digestion and aiding in correct folding. In coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES) and enhances IRES-mediated translation. SSB Protein, Human is the recombinant human-derived SSB protein, expressed by E. coli , with tag free. The total length of SSB Protein, Human is 408 a.a., with molecular weight of ~50 kDa.

Human

The SSB protein plays a crucial role by binding to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, providing protection against exonuclease digestion and facilitating their proper folding and maturation, as evidenced by various studies. Additionally, in the context of Coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES), thereby stimulating IRES-mediated translation. The protein further engages in interactions with DDX15 and may potentially interact with RUFY1, indicating its involvement in diverse cellular processes and highlighting its multifunctional nature.

Lupus La protein; Sjoegren syndrome type B antigen; SS-B

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized a 0.2 μm filtered solution of PBS, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.