protein

Syntaxin-7 Protein, Rat (HEK293, His)

HY-P73620

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

50;80;215;340;880;1400 USD

Syntaxin-7 Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

50;80;215;340;880;1400 USD

Syntaxin-7 protein is a central player in protein trafficking and membrane fusion events. It guides proteins from the plasma membrane to early endosomes, facilitates homotypic fusion of endocytic organelles, and mediates transport from early endosomes to late endosomes and lysosomes. Syntaxin-7 Protein, Rat (HEK293, His) is the recombinant rat-derived Syntaxin-7 protein, expressed by HEK293 , with N-His labeled tag. The total length of Syntaxin-7 Protein, Rat (HEK293, His) is 237 a.a., with molecular weight of ~30 kDa.

Rat

Syntaxin-7 Protein emerges as a key player in cellular processes related to protein trafficking and membrane fusion events. It is implicated in the trafficking of proteins from the plasma membrane to the early endosome (EE) and contributes to the homotypic fusion of endocytic organelles. Additionally, Syntaxin-7 plays a pivotal role in mediating endocytic trafficking from early endosomes to late endosomes and lysosomes. Interactions with VPS11, VPS16, VPS18, and VPS33A underscore its involvement in endosomal dynamics. Furthermore, Syntaxin-7 forms a SNARE complex with VTI1B, STX8, and VAMP8, crucial for the homotypic fusion of late endosomes. It is also a component of the SNARE complex with STX7, STX8, VAMP7, and VTI1B, essential for heterotypic fusion of late endosomes with lysosomes. The interaction with TPC1 further suggests its participation in intricate cellular processes. Investigating the detailed mechanisms underlying Syntaxin-7's interactions and functions could provide valuable insights into its role in membrane trafficking and fusion events within the endocytic pathway.

STX7; Syntaxin 7; syntaxin-7

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.