protein

Thrombin Receptor/PAR1 Protein, Human (HEK293, His)

HY-P73612

5 μg;10 μg;50 μg;100 μg

55;85;220;350 USD

Thrombin Receptor/PAR1 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

55;85;220;350 USD

The thrombin receptor/PAR1 protein is a high-affinity receptor for activated thrombin that is coupled to G proteins to stimulate phosphoinositide hydrolysis. This signaling mechanism suggests its involvement in platelet activation, which is critical for hemostasis and thrombosis. Thrombin Receptor/PAR1 Protein, Human (HEK293, His) is the recombinant human-derived Thrombin Receptor/PAR1 protein, expressed by HEK293 , with C-His labeled tag.

Human

Thrombin Receptor/PAR1 Protein serves as a high-affinity receptor for activated thrombin, forming a coupling with G proteins that, in turn, stimulate phosphoinositide hydrolysis. This intricate signaling mechanism suggests its potential involvement in platelet activation, a critical process in hemostasis and thrombosis. Furthermore, Thrombin Receptor/PAR1 Protein may play a role in vascular development, indicating its significance in the complex regulatory pathways that govern blood vessel formation and maintenance. The dual functions of this receptor highlight its role in both hemostatic processes and broader aspects of vascular biology, underscoring its importance in maintaining cardiovascular homeostasis.

Cf2r; CF2RHTR; F2R; HTR; PAR1; Protease-Activated Receptor 1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.