protein

TIE-2 Protein, Mouse (HEK293, His)

HY-P73610

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;75;165;260;850;1500 USD

TIE-2 Protein, Mouse (HEK293, His)

Protein

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;75;165;260;850;1500 USD

TIE-2 Protein, Mouse (HEK293, His) belongs to the receptor tyrosine kinase family and functions as a receptor for Angiopoietin-1 (Ang1). Ang1 bridges TIE-2 at cell-cell contacts, resulting in trans-association of TIE-2 in the presence of cell-cell contacts. TIE-2 activation promotes vessel assembly and maturation by mediating survival signals for EC and regulating the recruitment of pericytes. TIE-2 maintains the vascular integrity of mature vessels by enhancing endothelial barrier function and inhibiting apoptosis of endothelial cells. TIE-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TIE-2 protein, expressed by HEK293 , with C-His labeled tag.