protein

Tissue Factor Protein, Rabbit (HEK293, His)

HY-P73594

5 μg;10 μg;50 μg;100 μg

50;80;225;380 USD

Tissue Factor Protein, Rabbit (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

50;80;225;380 USD

Tissue Factor Protein initiates blood coagulation by binding to coagulation factors. It activates clotting cascades and interacts with cells to promote thrombosis and inflammation. Understanding Tissue Factor Protein's functions is crucial for developing treatments for cardiovascular diseases and blood disorders. Tissue Factor Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived Tissue Factor protein, expressed by HEK293 , with C-His labeled tag. The total length of Tissue Factor Protein, Rabbit (HEK293, His) is 218 a.a., with molecular weight of ~26.4 kDa.

Rabbit

Tissue Factor (TF) serves as the initiator of blood coagulation, creating a complex with circulating factor VII or VIIa. This [TF:VIIa] complex, through specific limited proteolysis, activates factors IX or X. In normal hemostasis, TF plays a pivotal role by instigating the assembly and propagation of the coagulation protease cascade on the cell surface. Furthermore, TF interacts with HSPE, and this interaction, hindered by heparin, facilitates the generation of activated factor X, ultimately contributing to the activation of coagulation in the presence of activated factor VII. This underscores the intricate involvement of TF in the regulatory processes of blood clotting.

CD142; Coagulation Factor III; F3; TF; TFA; Tissue Factor

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.