protein

TrkA Protein, Canine (HEK293, Fc)

HY-P73578

5 μg;10 μg;50 μg;100 μg;500 μg

40;65;180;290;870 USD

TrkA Protein, Canine (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg

40;65;180;290;870 USD

TrkA Protein (isoform 3) belongs to the nerve growth factor receptor family and can promote angiogenesis and has carcinogenic activity when overexpressed. TrkA Protein (isoform 3) antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes the differentiation of neuronal precursors. TrkA Protein, Canine (HEK293, Fc) is the recombinant canine-derived TrkA protein, expressed by HEK293 , with N-hFc labeled tag.

Canine

TrkA Protein (isoform 3) is only expressed in undifferentiated early neural progenitor cells, human neuroblastoma (NBs), and other subsets of neural crest-derived tumors, and can promote angiogenesis and exhibit carcinogenic activity when overexpressed. TrkA Protein (isoform 3) antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes the differentiation of neuronal precursors [1] .

High affinity nerve growth factor receptor; Trk-A; NTRK1; MTC; TRK

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.