protein

VE-Cadherin Protein, Rat (HEK293, His)

HY-P73557

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

VE-Cadherin Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

VE-cadherin is critical for cellular functions such as β-catenin binding and signaling receptor activity, and is involved in processes such as cell-cell junction organization and vascular maturation. It is predicted to localize in cell-cell junctions and nuclei, serving as a biomarker for pulmonary hypertension. VE-Cadherin Protein, Rat (HEK293, His) is the recombinant rat-derived VE-Cadherin protein, expressed by HEK293 , with C-His labeled tag. The total length of VE-Cadherin Protein, Rat (HEK293, His) is 561 a.a., with molecular weight of ~80-95 kDa.

Rat

VE-Cadherin Protein is predicted to play a crucial role in various cellular functions, including beta-catenin binding, enzyme binding, and signaling receptor binding activities. It is anticipated to be involved in processes such as cell-cell junction organization, regulation of protein modification, and regulation of protein-containing complex assembly. VE-Cadherin is predicted to function upstream of blood vessel maturation, cell-cell adhesion, and negative regulation of cell population proliferation. The protein is expected to be located in cell-cell junctions, the external side of the plasma membrane, and the nucleus, and it may participate in catenin complex formation. With predicted activity in adherens junctions and bicellular tight junctions, VE-Cadherin serves as a biomarker for pulmonary hypertension. Its human ortholog, cadherin 5 (CDH5), shows biased expression in lung and heart tissues, highlighting its importance in cardiovascular and pulmonary contexts.

Cadherin-5; VE-cadherin; CD144; CDH5

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.