protein

VISTA/B7-H5 Protein, Rat (HEK293, Fc)

HY-P73546

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;55;150;260;730;1240 USD

VISTA/B7-H5 Protein, Rat (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;55;150;260;730;1240 USD

VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Rat (HEK293, Fc) is the recombinant rat-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VISTA/B7-H5 Protein, Rat (HEK293, Fc) is 159 a.a., with molecular weight of ~44.7 kDa.

Rat

VISTA/B7-H5 protein, functioning as an immunoregulatory receptor, plays a pivotal role in inhibiting the T-cell response, as established in various studies. Additionally, it may contribute to the differentiation of embryonic stem cells by inhibiting BMP4 signaling, showcasing its potential role in developmental processes. Moreover, VISTA/B7-H5 has been implicated in stimulating MMP14-mediated MMP2 activation, suggesting a regulatory function in matrix metalloproteinase-mediated processes. This multifaceted role underscores the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics, revealing its potential impact across diverse biological contexts.

Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.