protein

VEGF-DD Protein, Rat (HEK293, Fc)

HY-P73475

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

36;100;280;480;1200;1800 USD

VEGF-DD Protein, Rat (HEK293, Fc)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

36;100;280;480;1200;1800 USD

VEGF-DD, a growth factor, stimulates proliferation, migration, and vessel permeability. It is crucial for vascular development and maintenance of lymphatic endothelium. VEGF-DD binds and activates VEGFR-3, initiating essential signaling pathways. Structurally, it forms a non-covalent homodimer, playing an intricate role in vascular processes. VEGF-DD Protein, Rat (HEK293, Fc) is the recombinant rat-derived VEGF-DD protein, expressed by HEK293 , with N-hFc labeled tag. The total length of VEGF-DD Protein, Rat (HEK293, Fc) is 117 a.a., with molecular weight of ~50 kDa.

Rat

VEGF-DD, a growth factor with pivotal roles in angiogenesis, lymphangiogenesis, and endothelial cell dynamics, demonstrates the ability to stimulate cellular proliferation and migration, along with influencing blood vessel permeability. Its significance extends to the formation of both venous and lymphatic vascular systems during embryogenesis, as well as the maintenance of differentiated lymphatic endothelium in adults. Functionally, VEGF-DD binds to and activates the VEGFR-3 (Flt4) receptor, initiating crucial signaling pathways for vascular development and homeostasis. Structurally, VEGF-DD exists as a homodimer with a non-covalent and antiparallel configuration, emphasizing its intricate role in orchestrating complex vascular processes.

Vascular endothelial growth factor D; VEGF-D; FIGF

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.